A synergistic approach to anion antiport.

نویسندگان

  • Stephen J Moore
  • Matthew G Fisher
  • Masafumi Yano
  • Christine C Tong
  • Philip A Gale
چکیده

A synergistic approach to Cl(-)/HCO(3)(-) antiport has been demonstrated in POPC lipid bilayers using an ion selective electrode assay showing that, when using combinations of carriers each optimised for a particular component of the transport process, enhanced rates of transport are observed.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells.

The effects of compounds previously described to inhibit anion transport were tested for their ability to inhibit anion antiport in Vero cells as measured by uptake of 36Cl- by chloride self-exchange and as bicarbonate-linked uptake of 22Na+. While 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid inhibited both processes, ethacrynic acid and probenecid selectively inhibited the uptake of 36Cl-....

متن کامل

AN APPROACH TO THE A RING OF VITAMIN D ANALOGUES VIA SEQUENTIAL CARBOMETALATION/ ANION CAPTURE

An intramolecular palladium catalysed carbometalation followed by anion capture achieves construction of a model comprised of the A ring of Vitamin D oxygen analogues.

متن کامل

Divalent Anion Transport in Crustacean and Molluscan Gastrointestinal Epithelia

A novel invertebrate gastrointestinal transport mechanism has been shown to couple chloride/sulfate exchange in an electrogenic fashion. In the lobster, Homarus americanus, the hepatopancreas, or digestive gland, exists as an outpocketing of the digestive tract, representing a single cell layer separating the gut lumen and an open circulatory system comprised of hemolymph. Investigations utiliz...

متن کامل

Prodigiosin is a chloride carrier that can function as an anion exchanger.

The natural product prodigiosin 1, often described as an H+/Cl- symport cotransporter, can transport Cl- across lipid vesicles via an anion exchange (or antiport) mechanism.

متن کامل

pH switchable anion transport by an oxothiosquaramide.

An oxothiosquaramide was shown to bind to chloride through hydrogen bonding interactions in DMSO and found to exhibit pH switchable choride transport across phospholipid bilayers via an antiport transport mechanism.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Dalton transactions

دوره 40 45  شماره 

صفحات  -

تاریخ انتشار 2011